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  • Dr. Stephen Archer - Research about Pulmonary Hypertension

    Published Wed Apr 27th 2016

    Learn about Pulmonary Hypertension - Video with Dr. Stephen Archer

    Pulmonary hypertension, high blood pressure in the lungs, is not just a chronic illness — it can also be fatal. Dr. Stephen Archer, the Head of Medicine at KGH and Queen’s University and a clinician-scientist, is working to better understand how to treat and potentially cure pulmonary hypertension by delving deep inside the human body, examining cell structures to find abnormalities that can cause this disease.

    Dr. Archer’s research in pulmonary hypertension revolves around the mitrochondria, what he refers to as the ‘power plants’ of the cell. “The mitochondria in patients with pulmonary hypertension are structurally abnormal,” he says. “We’ve been able to identify the particular protein that’s abnormal and target it with a small molecule to fix the problem.” He notes that the same therapy appears to also show promise in lung cancer treatments. Dr. Archer’s work in pulmonary hypertension was selected by the National Heart, Lung and Blood Institute as one of its Top Discoveries in 2010.