Research Interests

  • Mechanisms of nutrient sensing in the distal gastrointestinal tract by extrinsic sensory nerves
  • Role of nutrient sensing in distal gastrointestinal tract in presentation of irritable bowel syndrome

Models

  • Animal model to examine activation of colonic extrinsic sensory nerves by nutrient factors and modulation of this pathway by stress
  • Human colonic surgical resection tissue to examine activation of human afferent nerves by nutrient factors
  • Human colonic biopsies to examine activation of enteroendocrine cells by nutrient factors