Proposed Infrastructure

QCPU has 3 cores:

Core 1: Pre-clinical Discovery and Experimental Therapeutics
This core supports the creation of preclinical model of diseases and careful quantification of disease severity.

Model Creation Equipment

  • Hypoxia Chambers


Phenotyping Equipment


Advanced Imaging Equipment

  • Micro-CT system
  • Micro-SPECT system
  • Micro-PET system


Deep Phenotyping Equipment


Histology Equipment


Isolated Lung System for Mouse and Rat


Cell Culture Equipment

  • High performance cell culture system with integrated hoods, incubators, and biosafety cabinets
  • Electroporation System
  • Sony SH800 Cell Sorter (Level II capable)


Experimental Therapeutics Equipment

  • Automated Peptide Synthesizer
  • Electric Cell-Substrate Impedance Sensing (ECIS) System
  • The BioFlux System


Basic Lab Equipment

  • Basic laboratory equipment
  • Autoclave


Core 2 - Translational Research and Clinical Trials

Human Exercise and EKG Equipment

Human Cardiovascular Ultrasound System

Human Pulmonary Function Testing Equipment

Human Point of Care Equipment

  • Blood Gas Analyzer
  • Brain Natriuretic Peptide (BNP) Analyzer
  • Adrenergic Profiling Analyzer



Core 3 - Population Health

ICES and Clinical Trials Databases for PAH