* = courses that are one term in length. Courses are 3 credits unless otherwise stated
The flagship course entitled Translational Medicine will include faculty lectures, interactive patient sessions, and clinical observerships. In the experiential course, Profession of Medicine, students will attend weekly Medical Grand Rounds becoming immersed in the professional environment of medicine. The third course, Research Success Skills, will educate students about study design, as well as ethical and regulatory requirements for biomedical research.
|TMED* 800 Translational Medicine||
Students will be educated in the translation of medical knowledge from a variety of medical disciplines. Classroom sessions will be divided into a traditional lecture, followed by an interactive discussion and a 3-minute student presentation. Clinical observerships will involve direct placement within various clinics. Students will be expected to write a review article on the topic of their thesis research
|TMED 801 Profession of Medicine||
This course will immerse students in the professional learning environment of Medicine. Course content will consist of attendance at a minimum number of weekly Medical Grand Rounds, followed by facilitated small group discussions. Student seminars will be held during the winter term for presentation of thesis research proposals.
|TMED 802 Research Success Skills||
This course will provide the students with essential skills required to be a successful researcher. Instruction on study design, ethical and regulatory requirements for biomedical research will be provided through completion of online modules. A Library session will be included to teach strategies to search biomedical literature. Students will be expected to write a CIHR Canada Graduate Scholarship application and laboratory/research skills related to their thesis research will be evaluated.
Additional electives may be approved by the program director and students' supervisor, depending on the research interests of the student.
|TMED 811 Next Generation Sequencing||
This one-credit course will teach students the theoretical and practical basis of high-throughput genomics and transcriptomics. The course is a combination of classroom lectures, practical bench science and practical computing. Students will learn to design, implement and analyze an experiment using next generation sequencing technology and be expected to demonstrate these skills in the course assignments.
|BMED 862 Cellular Techniques||
This one-credit course is part of a suite of methodology courses being developed for the graduate program in Biomedical and Molecular Sciences intended to familiarize graduate students with the principles and practice of cutting edge technologies used in biomedical and molecular sciences research. The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used for protein and peptide analysis involved in biomedical research.
|BMED 865 Imaging Analysis||
This one-credit course is part of a suite of methodology courses being developed for the graduate program in Biomedical and Molecular Sciences intended to familiarize graduate students with the principals and practice of cutting edge technologies used for imaging analysis involved in biomedical and molecular sciences research. This particular course will introduce students to wide field epifluorescence microscopy, confocal microscopy, immunohistochemistry, imaging of live cells and fluorescence recovery after photobleaching.
|BMED 869 Reproduction||
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used in reproductive and developmental biology involved in biomedical and molecular sciences research. This specific offering of the course will focus on methods to study developmental toxicity. This unit will include an introductory lecture, hands on laboratory experience and a take home assignment.
|BMED 809* Principles and Drug Discovery and Development||
This is a problem-based course focusing on and consisting of discussions of receptor theory, mechanisms of drug action, drug metabolism, pharmacokinetics, pharmacogenetics and pharmacogenomics, and drug transport. The course comprises lectures, problem-solving discussions and seminars, based on recent literature.
|BMED 811* Advanced Molecular Biology||
This course concentrates on the molecular biology of mammalian models particularly mechanisms involved in human diseases. The human genome project, forensic analysis, DNA diagnostics of human diseases, models of transcriptional and growth regulation and cancer, DNA repair, RNA processing and translation are all discussed. Emphasis on recent findings and course materials will be drawn from current reviews.
|NSCI 844* Controversies in Neuroscience||
As insight regarding the human brain expands, so do issues such as what constitutes personhood, what drives the criminal mind, intelligence-enhancing drugs and end-of-life decisions, to name a few. Lead by experts who deal daily with such concerns, this course will focus weekly on a particular topic in neuroscience which impacts on society.
|EPID 803* Public Health System in Canada||
This course provides an overview of the public health system in Canada including the provision of health care services. The first section of the course provides a history and overview of the Canadian public health care system, including how health services are organized and financed, as well as an introduction to health policy. The second section of the course highlights health care delivery, focusing on federal and provincial health care delivery, and both major and specialized health care delivery systems.
|EPID 810* Controlled Clinical Trials||
This course will cover material relevant to the design and conduct of controlled clinical trials. Design topics will include methods used to achieve unbiased results with improved precision, such as adequate sample size, randomization, blinding, pre- and post-stratification, cross-over designs, placebos and the counting of relevant events. Attention will be given to the problem of conducting multi-centre clinical trials. Topics covered will include drafting of protocols, design of data forms, logistics of data flow, methods of follow-up, data management and quality control, periodic reporting, final data analysis and the production of final reports. Ethical issues and the role of randomized trials in clinical investigation will be discussed.
|PATH 822* Experimental Cancer Therapeutics||
The aim of this course is to introduce and discuss essential questions on the basic science of experimental therapeutics for the treatment of cancer. Topics will include discussions on: new drug development; molecular and signaling pathways involved in tumour genesis; challenges with existing cancer therapeutics; molecular approaches to profiling human cancer signatures; drug discovery and delivery; imaging, preclinical and clinical testing of novel therapies to assess efficacy and validate drug targets; and clinical trial results and the molecular basis for variability in tumour responses. A general theme for the course will be how to identify an experimental target or novel therapeutic, and translate the results into an improved therapy for the treatment of cancer.
|PATH 826* The Molecular Basis of Disease||
This course covers several diseases and integrates the genetic, biochemical, physiologic, anatomic, and general etiologic factors which play a role in the progression of each disease from its inception to death or recovery. The perspective will demonstrate that each disease is the result of an evolving interplay of genetic and environmental factors.