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Hi Jay,
Thanks for the great question, I was actually wondering that as well. Dr. Shukla mention's in the first paper I cited, how there needs to a longitudinal study looking as this connection to help identify why they seem to be connected. So really, even she doesn't know what the connection is. I did some reading and found that subcortical brain areas like the pyramidal tract and the basal ganglia-brainstem axis, are often the damaged areas and are involved in motor functions and sleep-wake cycles, which may explain why we see RLS in these patients. Here's the link if you want to read it yourself!…

Spencer Finn

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