Skip to main content

Name
Kiera Liblik

Tue, 11/16/2021 - 09:58

Dear Kyla,
Thank you for an excellent summary and discussion of last week's MGR. It seems that perioperative atrial fibrillation (AF) is gaining a lot of attention as of late, given the associated long-term morbidity and mortality (1-4). A recent review on the topic highlighted that age may play a role, as atrial fibrosis becomes more common with time (5). I wonder that if with enough information, we could better predict perioperative AF and, in turn, attempt to prevent it by administering anti-arrhythmic agents in the time leading up to surgery. Perhaps this could be used in conjunction with colchicine. Although, if the COP-AF trial is successful we may not need to look further!
Warm regards,
Kiera

1. Conen, D., Wang, M. K., Devereaux, P. J., Whitlock, R., McIntyre, W. F., Healey, J. S., ... & Lamy, A. (2021). New‐Onset Perioperative Atrial Fibrillation After Coronary Artery Bypass Grafting and Long‐Term Risk of Adverse Events: An Analysis From the CORONARY Trial. Journal of the American Heart Association, e020426.
2. Conen, D., Alonso-Coello, P., Douketis, J., Chan, M. T., Kurz, A., Sigamani, A., ... & Devereaux, P. J. (2020). Risk of stroke and other adverse outcomes in patients with perioperative atrial fibrillation 1 year after non-cardiac surgery. European heart journal, 41(5), 645-651.
3. Subramani, Y., El Tohamy, O., Jalali, D., Nagappa, M., Yang, H., & Fayad, A. (2021). Incidence, Risk Factors, and Outcomes of Perioperative Atrial Fibrillation following Noncardiothoracic Surgery: A Systematic Review and Meta-Regression Analysis of Observational Studies. Anesthesiology research and practice, 2021.
4. Wang, M. K., Meyre, P. B., Heo, R., Devereaux, P. J., Birchenough, L., Whitlock, R., ... & Conen, D. (2021). Short-term and long-term risk of stroke in patients with perioperative atrial fibrillation after cardiac surgery: Systematic review and meta-analysis. CJC Open.
5. Karamchandani, K., Khanna, A. K., Bose, S., Fernando, R. J., & Walkey, A. J. (2020). Atrial fibrillation: current evidence and management strategies during the perioperative period. Anesthesia & Analgesia, 130(1), 2-13.

Name
Kiera Liblik

Plain text

  • No HTML tags allowed.
  • Lines and paragraphs break automatically.
  • Web page addresses and email addresses turn into links automatically.