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Hi Dilakshan,

Thank you so much for your thought-provoking post. To answer your question, do I think the conflicting literature on colchicine treatment with AF would inform the clinical trials? I think this is a very hard question because some therapeutic interventions work differently for some people versus others. I believe there are a lot of unknowns about the causative effect of perioperative AF so predicting the outcome at this point would be almost impossible. To answer your second question, do I think this will add to the literature? Absolutely, in fact I think this is one of the most exciting aspects of the COP-AF coming to Kingston. We are going to have so much potential research and hopefully this can close the gap on dosing and treatments for AF.
I hope this answers your questions,

Thank you so much for a great post.

Kyla Tozer

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