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<div class="gva-breadcrumb-content"> <div id="block-gavias-financial-breadcrumbs" class="text-dark block gva-block-breadcrumb hidden-xs block-system block-system-breadcrumb-block no-title"> <div class="container"> <div class="breadcrumb-content-main"> <h2 class="page-title hide">This Month's TIME Showcase-Recent Publication by Dr. Paula James & Colleagues </h2> <div class=""> <div class="content block-content"> <div class="breadcrumb-links"> <div class="content-inner"> <nav class="breadcrumb " role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> <span class=""> / </span> </li> <li> </li> <li> This Month's TIME Showcase-Recent Publication by Dr. Paula James & Colleagues </li> <li></li> </ol> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div role="main" class="main main-page"> <div class="clearfix"></div> <div class="clearfix"></div> <div 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block-system-main-block no-title"> <div class="content block-content"> <!-- Start Display article for teaser page --> <!-- Start Display article for detail page --> <article data-history-node-id="1357" about="/news/months-time-showcase-recent-publication-dr-paula-james-colleagues" class="node node-detail node--type-article2 node--promoted node--view-mode-full clearfix"> <div class="post-block"> <div class="post-thumbnail post-"> <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <div class="item"> <img loading="lazy" src="/sites/deptmed/files/2022-12/Screen%20Shot%202022-12-01%20at%202.51.04%20PM.png" alt="From left: Dr. Charlie Hindmarch, Robbie Kloosterman, Dr. Paula James, Dr. Neil Renwick, Dr. Kathrin Tyryshkin" typeof="foaf:Image" /> </div> </div> <!-- <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <div class="item"> <img loading="lazy" src="/sites/deptmed/files/2022-12/Screen%20Shot%202022-12-01%20at%202.51.04%20PM.png" alt="From left: Dr. Charlie Hindmarch, Robbie Kloosterman, Dr. Paula James, Dr. Neil Renwick, Dr. Kathrin Tyryshkin" typeof="foaf:Image" /> </div> </div> --> </div> <div class="post-content"> <h1 class="post-title"><span class="field field--name-title field--type-string field--label-hidden">This Month's TIME Showcase-Recent Publication by Dr. Paula James & Colleagues </span> </h1> <div class="post-meta"> <span class="post-categories"> <div class="field field--name-field-post-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item">TIME News</div> <div class="field__item">TIME Showcase</div> </div> </span> | <span class="post-created"> 1 December 2022 </span> <!--| <span class="post-comment"> <a href="/news/months-time-showcase-recent-publication-dr-paula-james-colleagues/#comments"> Comments</a> </span>--> </div> <div class="node__content clearfix"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><strong>A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from type 1 VWD patients</strong></p> <p>Authors:</p> <p><em><strong><a>Robbie Kloosterman</a></strong>, <a>Matteo Zago-Schmitt</a>, <a>Julie Grabell</a>, <a>Lisa Ann Thibeault</a>, <a>Patricia D.A. Lima</a>, <a>Mackenzie L Bowman</a>, <strong><a>Kathrin Tyryshkin</a></strong>, <a><strong>Charles C. T. Hindmarch</strong>, </a><strong><a>Neil Renwick</a>, <a>Paula D. James</a></strong></em></p> <p>Journal: Blood Advances, Published-September 2022.</p> <p><a href="https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2022007884/486657/A-transcriptome-analysis-of-basal-and-stimulated">Read the full Article</a></p> <p><span><span><span><span><span><span><span><span><span><span><span>This research team, which includes </span></span></span><span><span><span>Drs. James, Hindmarch, Renwick, and Tyryshkin</span></span></span><span><span><span> successfully received an <strong>Inaugural TIME Incubator Grant </strong>worth $75K to support a project focused on understanding the transcriptional characterization of the response of endothelial cells from patients with Type 1 von Willebrand disease and normal controls to stimulation with a secretagogue. This work was the primary focus of the thesis research carried out by MSc student Robbie Kloosterman, who successfully defended his degree in April of 2021.</span></span></span><span><span><span> This is an excellent example of how a multidisciplinary translational research team can use TIME incubator grants to convert dollars into data! </span></span></span></span></span></span></span></span></span></span></span></p> </div> </div> <div id="node-single-comment"> </div> </div> </div> </article> <!-- End Display article for detail page --> </div> </div> </div> </div> </div> </div> <!-- Sidebar Left --> <!-- End Sidebar Left --> <!-- Sidebar Right --> <!-- End Sidebar Right --> </div> </div> </div> </div> </div> </div> <footer id="footer" class="footer"> <div class="footer-inner"> <div class="footer-center"> <div class="container"> <div class="row"> <div class="footer-first col-lg-3 col-md-3 col-sm-12 col-xs-12 column"> <div class="region region-footer-first"> <div id="block-queensfooterlogo-2" class="block block-block-content block-block-contentf665d6b6-d3bf-4022-bc0c-d81efa4c3c55 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qu_footer_branding"></section></div> </div> </div> </div> </div> <div class="footer-second col-lg-9 col-md-9 col-sm-12 col-xs-12 column"> <div class="region region-footer-second"> <div id="block-linkfooter" class="hidden-xs hidden-sm block block-block-content block-block-contente03afdfc-b255-481b-9605-5a0e153ccacf no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_schools"></section></div> </div> </div> </div> </div> <div class="footer-third col-lg-12 col-md-12 col-sm-12 col-xs-12 column"> <div class="region region-footer-third"> <div id="block-contactinfomschq" class="block block-block-content block-block-contentfc5b443f-0626-414c-bca6-320b99b79ec2 no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="site_contact_social"> <section> <p class="title">Contact Us</p> <ul class="contact"> <li> <a href="/contact-us"><i class="fas fa-home"></i>Department of Medicine, School of Medicine</a> </li> <li><i class="fas fa-phone"></i>(613) 533-2967</li> <li> <a href="mailto:medicine@queensu.ca"><i class="fas fa-envelope"></i>medicine@queensu.ca</a> </li> </ul> </section> </section></div> </div> </div> </div> </div> <div class="footer-four col-lg-12 col-md-12 col-sm-12 col-xs-12 column"> <div class="region region-footer-four"> <div id="block-partnerhospitals" class="block block-block-content block-block-content3e6e93eb-5ca8-4f18-8fba-05193424157d no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_hospitals"></section></div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="copyright"> <div class="container"> <div class="copyright-inner"> <div class="region region-copyright"> <div id="block-gavias-financial-copyright" class="block block-block-content block-block-content6a74724d-d485-4216-a560-962e52758fde no-title"> <div class="content block-content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><section id="qhs_copyright"></section></div> </div> </div> </div> </div> </div> </div> </footer> </div> <script src="/sites/deptmed/files/js/js_6_QyGfWg2j6QOqbpBix9JqKZ5rhrpYxmJ493JuGJ5gY.js?scope=footer&delta=0&language=en&theme=gavias_financial&include=eJxtj1EOgzAMQy9U6JFQ2oYqIzQoCdO4_fhYxTT26WfZlrMoxqL7BjzC7pJl3RgdA66oFVs-JmBUt_gLAr6cqS09_ZGhwpPApsSSl7QTF9T4h41ghm7jrNIcW-m5mRq0TMCxsiTgwfw4e-vdf9gwizhqt4zpLGY4rsUvdBs0BydzytYvXOQNjcVu2Q"></script> <script src="https://www.queensu.ca/resources/libraries/react/react.production.min.js" defer=""></script> <script src="https://www.queensu.ca/resources/libraries/react/react-dom.production.min.js" defer=""></script> <script src="https://www.queensu.ca/resources/emergencyalerts-v2/emergencyalerts.js" type="module" defer=""></script> <script src="/sites/deptmed/files/js/js_TS235XPB86Rc__3-_8UDrXuyLLsGHIlUorrwHEl7ua0.js?scope=footer&delta=4&language=en&theme=gavias_financial&include=eJxtj1EOgzAMQy9U6JFQ2oYqIzQoCdO4_fhYxTT26WfZlrMoxqL7BjzC7pJl3RgdA66oFVs-JmBUt_gLAr6cqS09_ZGhwpPApsSSl7QTF9T4h41ghm7jrNIcW-m5mRq0TMCxsiTgwfw4e-vdf9gwizhqt4zpLGY4rsUvdBs0BydzytYvXOQNjcVu2Q"></script> </body> </html>