Angioedema (or so-called Angioneurotic Angiodema) is one of the most frightening medical emergencies. Angioedema is defined as a localized swelling of the skin and/or mucosal tissues. It typically affects areas with loose connective tissues such as face, lips, mouth, throat, larynx, uvula, extremities, or genitalia. However, angioedema can affect internal organs, such as the brain or abdominal viscera, causing them to swell. In angioedema, tissues can rapidly swell, disfiguring the patient and causing pain.