The Gastrointestinal Diseases Research Unit (GIDRU), recognized internationally for its high-calibre research, is one of few sites worldwide that fully integrating preclinical and clinical gastrointestinal studies. Completed in 2006, GIDRU is located within Kingston General Hospital and houses state-of-the-art chemostat, metabolomic, and biobanking facilities. We conduct a wide range of basic science, as well as translational (bench-to-bedside) and reverse-translational studies (bedside-to-bench), advancing the well-being of Canadians and of patients throughout the world. We nurture strong collaborations with colleagues at Queen’s through the Translations in Medicine (TIME) network and with researchers nationally and internationally. Moreover, we continue to build for the future by attracting first-rate faculty and students from across the globe. Our investigators successfully compete for major external, peer-reviewed grants and many of our trainees go on to secure leading positions in academia, medicine, and industry.