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Researchers

QCPU was established as a cost-recovery funding model. We provide Queen’s researchers with the experience and access to cutting-edge technology to bring their research to the next level. Currently, QCPU boasts 10 SuperUsers, defined as users who purchase service in blocks of 208 (SuperUser A plan) or 104 (SuperUser B plan) hours/year. We serve 24 research groups across 10 departments, 3 faculties and 3 universities. QCPU scientists have assisted or mentored over 60 trainees, including research staff, medical students, post-doctoral fellows, graduate students and undergrads. QCPU has contributed to 18 publications in the past year. Additionally, we host 3 graduate student courses, i.e., BMED828, TMED801 and TMED811. QCPU is also home base for 5 Translational MEDicine (TMED) graduate students, 3 Post-docs, 2 QCPU research scientists and 2 Translational Institute of Medicine (TIME) scientists.

QCPU embodies research excellence and will ensure that Queen's research is recognized internationally as a center for translational research. We welcome clincians and researchers who are looking for opportunities to collaborate, whether through our clinic or research center. Please contact QCPU to start your next steps to collaboration!

 The team that helped create QCPU through CFI Funding

Investigator Department Specialization
Dr. Stephen Archer Cardiology Mitochondria Dynamics
Dr. Mark Ormiston  Biomedical and Molecular Sciences NK Cells and Pulmonary Hypertension
Dr. Donald Maurice  Biomedical and Molecular Sciences Cyclic Nucleotide Signaling
Dr. Christine D'Arsigny  Respirology Pulmonary Hypertension
Dr. Amer Johri  Cardiology Cardiac Ultrasound
Dr. Paula James  Hematology Bleeding Disorders
Dr. Denis O'Donnell  Respirology Respiratory mechanics
Dr. Diane Lougheed  Respirology / Public Health / ICES Asthama and cystic fibrosis
Dr. Alberto Neder  Respirology Cardio-circulatory and respiratoty interactions
Dr. Sean Taylor  Neurology Autonomic Profiling
Dr. Alastair Ferguson  Neurology Autonomic control centers
Dr. John Fisher   Respirology Cardiopulmonary genomics
Dr. Shetuan Zhang   Biomedical and Molecular Sciences Ion Channel Dynamics
Dr. Evangelos Michelakis Cardiology - University of Alberta Pulmonary Hypertension
Dr. Thenappan Thenappan  Cardiology - University of Minnesota Pulmonary Hypertension
Dr. Michael Adams Biomedical and Molecular Sciences Pathogenesis of vascular diseases

SuperUsers at QCPU

Dr. Stephan Archer
Medicine

Dr. Stephan Archer

He is a CIHR and CRC Tier 1 funded cardiologist and physician scientist and is the Scientific Director of QCPU. His research focus is on defining molecular mechanisms of oxygen sensing, mitochondrial biology and development of mitochondrial metabolic therapies for therapeutics for pulmonary hypertension (PH) and cancer.    

Dr. David Lillicrap
Pathology & Molecular Medicine

Dr. David Lillicrap

He is a CIHR and CRC Tier 1 funded researcher. His research explores the molecular aspects of blood coagulation in hopes that this research will lead to better ways to diagnose and treat patients with bleeding disorders. Lillicrap and his research team are using a combination of molecular technologies to improve the understanding of common inherited bleeding disorders, such as hemophilia and von Willebrand disease and identify cures. 

Dr. Mark Ormiston
Medicine / Surgery

Dr. Mark Ormiston

He is a young investigator who is funded by CIHR and a Tier 2 CRC. Dr. Ormiston serves on the management board of QCPU. He studies how impairment of a specific immune cell Natural Killer (NK) cell, may be critical to development of pulmonary hypertension and how targeting these cells may offer a new avenue for treatment. His team also works on techniques to isolate and genetically modify patient-derived stem cells, with the ultimate goal of creating tailored immune cell therapies that can reverse the vascular changes that affects the lungs of patients with pulmonary arterial hypertension (PAH).

 

Dr. Don Maurice
Biomedical and Molecular Sciences

Dr. Don Maurice

He is a CIHR funded researcher and serves on the management board of QCPU. The Maurice Lab studies the role of cyclic nucleotide (cAMP and cGMP) compartmentalization and cyclic nucleotide signaling in human arterial endothelial cells and arterial smooth muscle cells. Since virtually all cells are either directly or indirectly influenced by cAMP and or cGMP, this pathway represents a potential therapeutic target in multiple cardiovascular diseases, such as atherosclerosis and restenosis, and is also important for processes such as angiogenesis.     

Dr. Stephen Vanner
Medicine / GIDRU

Dr. Stephen Vanner

He is a CIHR funded researcher, and is scientific director of GIDRU, our Digestive Diseases Research Unit. He is also the scientific director of the Translational Institute of Medicine (TIME). He has subspecialty expertise in gastrointestinal motility disorders involving the lower GI tract including the small intestine, colon and anorectum and is director of the anorectal motility laboratory.  He has an established translational research program that examines mechanisms underlying pain signaling and motility in the gastrointestinal tract, relevant to irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Dr. Alan Lomax
Medicine / GIDRU

Dr. Alan Lomax

He is a CIHR funded researcher. His lab investigates how interactions between the microbiota, nervous system and the immune system can contribute to symptom generation in inflammatory bowel disease.  They also investigate the regulation of neurogenesis in the enteric nervous system.

Dr. David Reed
Medicine/ GIDRU

Dr. David Reed

He is a young investigator. His clinical interest is in gastrointestinal motility disorders. His research interest is how the interaction of luminal factors (e.g. dietary components) with stress or the microbiota modulates pain signaling and motility in disorders such as irritable bowel syndrome    

Dr. James Rutka
Neurology / University of Toronto

Dr. James Rutka

He is a CIHR and CRC funded researcher and is Chair of the Department of Surgery at the University of Toronto, his laboratory has focussed on two areas of related research regarding the astrocytoma (malignant brain tumors): 1) Cytoskeletal:matrix interactions, and 2) Cell cycle control mechanisms. In the first project, they we have been studying the role of the astrocyte-specific intermediate filament, glial fibrillary acidic protein, in astrocytoma morphology and signaling pathways. In the second, they have been determining the effects of inducing cyclin dependent kinase inhibitors on human astrocyotma tumorigenicity 

Dr. Robert Siemens
Urology

Dr. Robert Siemens

He is the Head of the Department of Urology at Queen’s University. His research focus is on urological oncology. His research endeavors have led to novel observations of the role of the tumour microenvironment and its interactions with the oncogenic drivers of malignant progression, with a specific interest in translating these findings to clinically effective cancer immunotherapy approaches. 

Dr. Amer Johri
Medicine

Dr. Amer Johri

He is a mid-career researcher funded by the Heart and Stroke Foundation. He serves on the management board of QCPU. He is also founder and director of the Cardiovascular Imaging Network at Queen's (CINQ). His research interests include interest is in 3D echocardiography, quality control in the echo lab, interventional echocardiography, and Hand Held Cardiac Ultrasound. He also has extensive experience in echo-guided CRT optimization and TEE guided percutaneous aortic valve replacement (TAVI).  Dr. Johri’s current research interests include the investigation of carotid intimal medial thickening as a surrogate to diagnose vulnerable coronary artery atherosclerotic plaques. 

Dr. David Maslove
Medicine / Critical Care

Dr. David Maslove

He is an NSERC funded young investigator and Clinician Scientist with the Department of Medicine and Critical Care Program. His research focuses on informatics, genomics, and the use of biomedical Big Data to address current challenges in Critical Care Medicine.