Skip to main content

Researchers

QCPU was established as a cost-recovery funding model. We provide Queen’s researchers with the experience and access to cutting-edge technology to bring their research to the next level. Currently, QCPU boasts 10 SuperUsers, defined as users who purchase service in blocks of 208 (SuperUser A plan) or 104 (SuperUser B plan) hours/year. We serve 24 research groups across 10 departments, 3 faculties and 3 universities. QCPU scientists have assisted or mentored over 60 trainees, including research staff, medical students, post-doctoral fellows, graduate students and undergrads. QCPU has contributed to 18 publications in the past year. Additionally, we host 3 graduate student courses, i.e., BMED828, TMED801 and TMED811. QCPU is also home base for 5 Translational MEDicine (TMED) graduate students, 3 Post-docs, 2 QCPU research scientists and 2 Translational Institute of Medicine (TIME) scientists.

QCPU embodies research excellence and will ensure that Queen's research is recognized internationally as a center for translational research. We welcome clincians and researchers who are looking for opportunities to collaborate, whether through our clinic or research center. Please contact QCPU to start your next steps to collaboration!

 The team that helped create QCPU through CFI Funding

Investigator Department Specialization
Dr. Stephen Archer Cardiology Mitochondria Dynamics
Dr. Mark Ormiston  Biomedical and Molecular Sciences NK Cells and Pulmonary Hypertension
Dr. Donald Maurice  Biomedical and Molecular Sciences Cyclic Nucleotide Signaling
Dr. Christine D'Arsigny  Respirology Pulmonary Hypertension
Dr. Amer Johri  Cardiology Cardiac Ultrasound
Dr. Paula James  Hematology Bleeding Disorders
Dr. Denis O'Donnell  Respirology Respiratory mechanics
Dr. Diane Lougheed  Respirology / Public Health / ICES Asthama and cystic fibrosis
Dr. Alberto Neder  Respirology Cardio-circulatory and respiratoty interactions
Dr. Sean Taylor  Neurology Autonomic Profiling
Dr. Alastair Ferguson  Neurology Autonomic control centers
Dr. John Fisher   Respirology Cardiopulmonary genomics
Dr. Shetuan Zhang   Biomedical and Molecular Sciences Ion Channel Dynamics
Dr. Evangelos Michelakis Cardiology - University of Alberta Pulmonary Hypertension
Dr. Thenappan Thenappan  Cardiology - University of Minnesota Pulmonary Hypertension
Dr. Michael Adams Biomedical and Molecular Sciences Pathogenesis of vascular diseases

SuperUsers at QCPU

Dr. Stephan Archer
Medicine

Dr. Stephan Archer

He is a CIHR and CRC Tier 1 funded cardiologist and physician scientist and is the Scientific Director of QCPU. His research focus is on defining molecular mechanisms of oxygen sensing, mitochondrial biology and development of mitochondrial metabolic therapies for therapeutics for pulmonary hypertension (PH) and cancer.    

Dr. David Lillicrap
Pathology & Molecular Medicine

Dr. David Lillicrap

He is a CIHR and CRC Tier 1 funded researcher. His research explores the molecular aspects of blood coagulation in hopes that this research will lead to better ways to diagnose and treat patients with bleeding disorders. Lillicrap and his research team are using a combination of molecular technologies to improve the understanding of common inherited bleeding disorders, such as hemophilia and von Willebrand disease and identify cures. 

Dr. Stephen Vanner
Medicine / GIDRU

Dr. Stephen Vanner

He is a CIHR funded researcher, and is scientific director of GIDRU, our Digestive Diseases Research Unit. He is also the scientific director of the Translational Institute of Medicine (TIME). He has subspecialty expertise in gastrointestinal motility disorders involving the lower GI tract including the small intestine, colon and anorectum and is director of the anorectal motility laboratory.  He has an established translational research program that examines mechanisms underlying pain signaling and motility in the gastrointestinal tract, relevant to irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Dr. James Rutka
Neurology / University of Toronto

Dr. James Rutka

He is a CIHR and CRC funded researcher and is Chair of the Department of Surgery at the University of Toronto, his laboratory has focussed on two areas of related research regarding the astrocytoma (malignant brain tumors): 1) Cytoskeletal:matrix interactions, and 2) Cell cycle control mechanisms. In the first project, they we have been studying the role of the astrocyte-specific intermediate filament, glial fibrillary acidic protein, in astrocytoma morphology and signaling pathways. In the second, they have been determining the effects of inducing cyclin dependent kinase inhibitors on human astrocyotma tumorigenicity 

Dr. Robert Siemens
Urology

Dr. Robert Siemens

He is the Head of the Department of Urology at Queen’s University. His research focus is on urological oncology. His research endeavors have led to novel observations of the role of the tumour microenvironment and its interactions with the oncogenic drivers of malignant progression, with a specific interest in translating these findings to clinically effective cancer immunotherapy approaches. 

Dr. Don Maurice
Biomedical and Molecular Sciences

Dr. Don Maurice

He is a CIHR funded researcher and serves on the management board of QCPU. The Maurice Lab studies the role of cyclic nucleotide (cAMP and cGMP) compartmentalization and cyclic nucleotide signaling in human arterial endothelial cells and arterial smooth muscle cells. Since virtually all cells are either directly or indirectly influenced by cAMP and or cGMP, this pathway represents a potential therapeutic target in multiple cardiovascular diseases, such as atherosclerosis and restenosis, and is also important for processes such as angiogenesis.     

Dr. David Maslove - TIME Grant 2019
Medicine / Critical Care

Dr. David Maslove - TIME Grant 2019

He is an NSERC funded young investigator and Clinician Scientist with the Department of Medicine and Critical Care Program. His research focuses on informatics, genomics, and the use of biomedical Big Data to address current challenges in Critical Care Medicine.    

Dr. Paula James - TIME Grant 2019
Medicine / Pathology and Molecular Medicine

Dr. Paula James - TIME Grant 2019

Dr. Paula James is the Graduate Program Director for the Translational Medicine Graduate Program and Professor in the Department of Medicine, with cross-appointments to Pathology & Molecular Medicine and Pediatrics. She  is a Principal Investigator in the Clinical and Molecular Hemostasis Research Group at Queen’s University with an active basic and clinical research program investigating the genetic basis of inherited bleeding disorders as well as the quantitation of bleeding symptoms. In May 2015, the Let’s Talk Period website and aligned social media accounts were launched to increase knowledge about abnormal bleeding.

 

Dr. David Reed  - TIME Grant 2019
Medicine/ GIDRU

Dr. David Reed - TIME Grant 2019

He is a young investigator. His clinical interest is in gastrointestinal motility disorders. His research interest is how the interaction of luminal factors (e.g. dietary components) with stress or the microbiota modulates pain signaling and motility in disorders such as irritable bowel syndrome    

Dr. Amer Johri - TIME Grant 2019
Medicine

Dr. Amer Johri - TIME Grant 2019

He is a mid-career researcher funded by the Heart and Stroke Foundation. He serves on the management board of QCPU. He is also founder and director of the Cardiovascular Imaging Network at Queen's (CINQ). His research interests include interest is in 3D echocardiography, quality control in the echo lab, interventional echocardiography, and Hand Held Cardiac Ultrasound. He also has extensive experience in echo-guided CRT optimization and TEE guided percutaneous aortic valve replacement (TAVI).  Dr. Johri’s current research interests include the investigation of carotid intimal medial thickening as a surrogate to diagnose vulnerable coronary artery atherosclerotic plaques. 

Dr. Rachel Holden - TIME Grant 2020
Medicine / Biomedical and Molecular Sciences

Dr. Rachel Holden - TIME Grant 2020

Dr. Rachel M. Holden is a nephrologist and an Associate Professor in the Department of Medicine with a cross-appointment to the Department of Biomedical and Molecular Sciences at Queen's University.  She and her associates study basic mechanisms of vascular calcification in chronic kidney disease.  A focus of her research program is clinical, basic and translational aspects of vitamin K metabolism and specifically the role of vitamin K in the inhibition of vascular calcification.  Her clinical interests include mineral bone disorders in chronic kidney disease and hemodialysis patients.