Dr. Rachel M. Holden is a nephrologist and a Professor in the Department of Medicine with a cross-appointment to the Department of Biomedical and Molecular Sciences at Queen's University.  She joined the faculty in 2001.  

She currently holds a Clinician Scientist award.  Dr. Holden and her associates study basic mechanisms of vascular calcification in chronic kidney disease.  A focus of her research program is clinical, basic and translational aspects of vitamin K metabolism and specifically the role of vitamin K in the inhibition of vascular calcification.

Dr. Holden's clinical interests include mineral bone disorders in chronic kidney disease and hemodialysis patients.