Whether investigating therapeutic response in a human subject or a mouse model of disease, getting the most information from every precious sample is a priority in clinical and research studies alike. Mass cytometry with Helios™ uses CyTOF® technology to enable deep profiling of translational and clinical research samples across a range of cell surface and intracellular markers. Designed to significantly reduce signal overlap, mass cytometry empowers researchers to simultaneously interrogate cellular phenotypes, function and signaling status in higher dimension than traditional fluorescence methods.