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class="column-content-inner"> <div class="column-content "><p>The TIME Core Facility (formerly known as the Queen’s CardioPulmonary Unit; QCPU) has significantly and intentionally expanded to benefit the broader research community! Our almost 10,000 sq ft facility includes over $25M in state-of-the-art research infrastructure and is supported by a team of 9 scientists. Our equipment and team is all under one roof – the BioSciences Complex, found in the heart of Queen’s Campus.</p> <p>Our laboratories and their services are as follows:</p> <div> <h3>Small Animal Imaging Laboratory</h3> <p>Advanced preclinical imaging and radiotracer support for small-animal research.</p> <ul style="margin-bottom: 0;"> <li>CT, PET, SPECT and optical imaging using the MiLabs VECTor7/CT platform</li> <li>Radiotracer labelling</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/small-animal-imaging">Explore Small Animal Imaging →</a></p> <h3>Flow Cytometry & Cell Culture</h3> <p>Integrated cellular analysis, cell sorting and in vitro experimentation supported by advanced cytometry and cell-culture technologies.</p> <ul style="margin-bottom: 0;"> <li>Spectral flow cytometry and cell sorting</li> <li>Nanoparticle quantification and cytometry</li> <li>Custom cell culture services</li> <li>Proliferation assays and transfection</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/flow-cytometry-cell-culture">Explore Flow Cytometry & Cell Culture →</a></p> <h3>Small Particles</h3> <ul style="margin-bottom: 0;"> <li>Nanoparticle imaging – ONI Nanoimager</li> <li>Nanoparticle quantification and cytometry – Beckman Coulter CytoFLEX nano</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/small-particle">Explore Small Particles →</a></p> <h3>Genomics & Molecular Biology Laboratory</h3> <ul style="margin-bottom: 0;"> <li>Molecular and protein quantification – Agilent TapeStation 4150</li> <li>Multiplex ELISAs – Luminex MagPix</li> <li>RNA and DNA extraction</li> <li>Next-generation library construction</li> <li>Sequencing – Oxford Nanopore PromethION 2 Integrated, GridION and MinION</li> <li>qRT-PCR – Bio-Rad OPUS Real-Time PCR System</li> <li>Biobanking</li> <li>Multi-omics – Leica Cell DIVE with BAB automation</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/genomics">Explore Genomics & Molecular Biology →</a></p> <h3>Microscopy</h3> <ul style="margin-bottom: 0;"> <li>Widefield microscopy – Leica Mica with live-cell imaging</li> <li>Two-photon confocal microscopy with FALCON – Leica SP8 System</li> <li>Tau-contrast confocal microscopy – Leica Stellaris Confocal Microscope with SpectraPlex</li> <li>Hyperplexed imaging – Leica Stellaris Confocal Microscope with SpectraPlex</li> <li>Transmission electron microscopy – Delong LVEM25 with TEM, STEM and SEM modes and Bruker Energy Dispersive X-Ray Spectroscopy</li> <li>Scanning electron microscopy – Delong LVEM25 with TEM, STEM and SEM modes and Bruker Energy Dispersive X-Ray Spectroscopy</li> <li>Nanoparticle imaging, quantification and cytometry – ONI Nanoimager and Beckman Coulter CytoFLEX nano</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/microscopy">Explore Microscopy →</a></p> <h3>Spatialomics</h3> <ul style="margin-bottom: 0;"> <li>Multi-omics – Leica Cell DIVE with BAB automation</li> <li>Tau-contrast confocal microscopy – Leica Stellaris Confocal Microscope with SpectraPlex</li> <li>Hyperplexed imaging – Leica Stellaris Confocal Microscope with SpectraPlex</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/spatialomics">Explore Spatialomics →</a></p> <h3>Histology</h3> <ul style="margin-bottom: 0;"> <li>Histology services, including processing and embedding – Leica HistoCore Suite</li> <li>Standard and special staining</li> <li>Transmission electron microscopy – Delong LVEM25 with TEM, STEM and SEM modes and Bruker Energy Dispersive X-Ray Spectroscopy</li> <li>Scanning electron microscopy – Delong LVEM25 with TEM, STEM and SEM modes and Bruker Energy Dispersive X-Ray Spectroscopy</li> </ul> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/histology">Explore Histology →</a></p> <h3>Biostatistics & Bioinformatics</h3> <p>Integrated statistical and computational support for study design, data analysis, high-throughput sequencing, multi-omics and reproducible research.</p> <p style="margin-top: 10px; margin-bottom: 30px;"><a href="https://deptmed.queensu.ca/research/translational-institute-medicine/research-services/core-facility/biostatistics">Explore Biostatistics & Bioinformatics →</a></p> </div></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="gbb-row-wrapper"> <div class=" gbb-row bg-size-cover" style="padding-top:30px; background-color:#58595B" > <div class="bb-inner remove_padding_top"> <div class="bb-container container-fw"> <div class="row"> <div class="row-wrapper clearfix"> <div class="gsc-column col-lg-8 col-md-8 col-sm-12 col-xs-12"> <div class="column-inner bg-size-cover " > <div class="column-content-inner"> <div class="column-content text-white-all "><div style="padding-left: 40px;"> <h2>Core Facility pricing</h2> <p>TIME offers hourly rates and annual SuperUser packages, with eligible discounts for Department of Medicine members and early-career investigators. 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