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hide">Spatialomics </h2> <div class=""> <div class="content block-content"> <div class="breadcrumb-links"> <div class="content-inner"> <nav class="breadcrumb " role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> <span class=""> / </span> </li> <li> <a href="/research">Research</a> <span class=""> / </span> </li> <li> <a href="/research/translational-institute-medicine">Translational Institute of Medicine (TIME)</a> <span class=""> / </span> </li> <li> <a href="/research/translational-institute-medicine/research-services">Research Services</a> <span class=""> / </span> </li> <li> <a href="/research/translational-institute-medicine/research-services/core-facility">Core Facility</a> <span class=""> / </span> </li> <li> </li> <li> Spatialomics </li> <li></li> </ol> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div role="main" class="main main-page"> <div class="clearfix"></div> <div class="clearfix"></div> <div class="clearfix"></div> <div id="content" class="content content-full"> <div class="container"> <div class="content-main-inner"> <div class="row"> <div id="page-main-content" class="main-content col-xs-12 col-md-8 sb-r "> <div class="main-content-inner"> <div class="content-main"> <div class="region region-content"> <div id="block-gavias-financial-content" class="block block-system block-system-main-block no-title"> <div class="content block-content"> <!-- Start Display article for detail page --> <article data-history-node-id="1690" typeof="schema:WebPage" class="node node--type-page node--view-mode-full"> <header> <div class="container"> <div class="widget gsc-heading align-left style-1 small text-dark "> <h1 class="title"><span><span property="schema:name" class="field field--name-title field--type-string field--label-hidden">Spatialomics</span> </span></h1> <div class="line"><span class="one"></span><span class="second"></span><span class="three"></span></div> </div> </div> </header> <div class="node__content clearfix"> <div property="schema:text" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The TIME Core Spatialomics platform integrates molecular biology, histology, microscopy and flow cytometry capabilities to support high-dimensional, spatially resolved analysis of tissues and cellular environments.</p> <p>Led by Dr. Doug Quilty, the platform combines advanced imaging, multiplexed molecular profiling and analysis tools to help researchers connect molecular information with spatial context and gain deeper insight into complex biological systems.</p> <h2>Spatialomics Capabilities</h2> <p>TIME Core supports advanced spatial biology workflows using integrated imaging and molecular technologies.</p> <p><strong>Equipment includes:</strong></p> <ul> <li>Multi-omics imaging – Leica Cell DIVE with BAB automation</li> <li>Tau-contrast confocal microscopy – Leica Stellaris Confocal Microscope with SpectraPlex</li> <li>Hyperplexed imaging – Leica Stellaris Confocal Microscope with SpectraPlex</li> </ul> <h2>Leica Cell DIVE</h2> <p>The Leica Cell DIVE platform supports highly multiplexed antibody-based spatial biology, enabling researchers to analyze more than 100 markers within a single tissue section through automated staining and imaging.</p> <p>Workflows can also be customized to incorporate RNA in situ hybridization probes where appropriate.</p> <h3>Research applications</h3> <ul> <li>Highly multiplexed spatial profiling</li> <li>Tissue microenvironment analysis</li> <li>Cell-type and biomarker mapping</li> <li>Spatial analysis of protein expression</li> <li>Integrated protein and RNA workflows</li> <li>Translational tissue-based research</li> </ul> <h3>Sample types</h3> <p>The platform supports tissue sections from human, mouse and rat samples mounted on standard Fisher Permafrost charged slides. Antigen retrieval requirements may vary by project, and workflows can be customized based on tissue type and research objectives.</p> <p><a href="https://www.leica-microsystems.com/products/light-microscopes/p/cell-dive/">Learn more about the Leica Cell DIVE platform</a></p> <h2>Pricing and Booking</h2> <h3>Pricing</h3> <p>Pricing is determined on a project-by-project basis and depends on factors including the number and size of tissue samples, program run length and number of antibodies required.</p> <h3>How to book</h3> <p>Contact the TIME Core team by email for projects requiring Spatialomics equipment or scientist support.</p> <h2>Planning your project</h2> <h3>Considering a spatial biology study?</h3> <p>Contact the TIME Core team to discuss your research question, tissue type, marker panel and project requirements. The team can help determine the most appropriate workflow and level of support for your study.</p> <p><strong>Contact:</strong> Dr. Doug Quilty</p> </div> </div> </article> </div> </div> </div> </div> </div> </div> <!-- Sidebar Left --> <!-- End Sidebar Left --> <!-- Sidebar Right --> <div class="col-lg-4 col-md-4 col-sm-12 col-xs-12 sidebar sidebar-right theiaStickySidebar"> <div class="sidebar-inner"> <div class="region region-sidebar-right"> <nav role="navigation" aria-labelledby="block-mainnavigation-28-menu" id="block-mainnavigation-28" class="block block-menu navigation menu--main"> <h2 id="block-mainnavigation-28-menu"><span><a href="/research/translational-institute-medicine/research-services/core-facility" class="menu-item--active-trail" data-drupal-link-system-path="node/1684">Core Facility</a></span></h2> <div class="block-content"> <div class="gva-navigation"> <ul class="clearfix gva_menu gva_menu_main"> <li class="menu-item menu-item--expanded menu-item--active-trail"> <a 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